Central Plains is a regional conference of Mennonite Church USA.
In the year 2000 Mennonite Mission Network, the Colombia Mennonite Church (IMCOL), and Central Plains Mennonite Conference formed the Ecuador Partnership, which focuses on Mennonite church development and indigenous ministries. In 2014 IMCOL invited Central Plains Mennonite Conference and Mennonite Mission Network to also partner together in Venezuela, supporting leadership development and church-planting ministries.